Complex Regional Pain Syndrome Type 1 (CRPS-I)

The study is for an oral investigational medication that may help improve CRPS symptoms.

Complex Regional Pain Syndrome (CRPS) is a chronic condition that causes intense pain – usually in the arms, hands, legs, or feet. CRPS often develops after an injury or trauma (such as an ankle fracture, wrist fracture, or surgery). However, the pain associated with CRPS is usually much greater than the original injury.

Symptoms of CRPS include:

• Intense burning pain
• Dramatic changes in skin temperature, colour, or texture
• Extreme skin sensitivity
• Swelling or stiffness in the affected area

Eligibility

If you suspect you have Complex Regional Pain Syndrome (CRPS), or have been diagnosed with CRPS within the past 6 months, you may qualify for the CREATE-1 Clinical Study. If you can answer “Yes” to the following questions, you may be eligible for the CREATE-1

Did your pain develop following an injury or surgery within the past year?

• Is your pain in either one upper limb (arm, wrist or hand), or one lower limb (leg, ankle or foot)?
• Can your pain be linked to an injury, trauma, or surgery?
• Are you able to attend required visits at your local study centre over a 6 – 7 month period?
• If you choose to join the study, you will receive all study-related care at no cost, and your CRPS condition and overall health will be closely monitored by a team of physicians and study staff. As a study participant, you will be asked to meet with your study doctor up to 13 times over a 6 – 7 month period. You may also be compensated for your time and travel to attend these visits.

ClinicalTrials.gov Link: NCT02504008

This trial has now ended.